Atomic Force Microscopy

Atomic force microscopy (AFM) is a powerful imaging and characterisation technique at the nanometre scale. Its principle is based on the interaction of a nanotip with the surface of a sample. AFM provides access to a large number of parameters: primarily nanometre-scale topography, but also local mechanical, electrical and magnetic properties.

image obtenue par AFM d'une coupe de peau : les fibres de collagène sont visibles

Assests of Atomic Force Microscopy AFM

  • Topographical analyses (profilometry) on areas of several µm² with lateral spatial resolution up to approximately 3 nm and vertical resolution of around 0.1 nm.
  • Surface characterisation of materials by measuring surface roughness, hardness and elasticity in the same observed area.
  • Characterisation of thin films and coatings: thickness and adhesive properties.

Measurements and analyses using atomic force microscopy (AFM)

Novitom's expertise in AFM analysis

  • Meticulous preparation of experimental conditions, tailored to each type of sample.
  • Development of measurement protocols for fragile samples such as biological samples, including skin and hair.
  • Original experimental approaches, for example for collagen quality assessment using AFM images combined with small-angle X-ray scattering.
  • Customised measurement and analysis services.

Types d’échantillons

  • Biological materials: thin sections of skin or other tissue, hair, nails, teeth
  • All types of materials: metals, composites, ceramics, glass, semiconductors

Further reading regarding AFM analysis

Anti-aging skincare seen through collagen fibres organisation

Anti-aging skincare seen through collagen fibres organisation

Novitom has developed an original test based on the…