Solid dosage forms

State-of-the-art technologies at the service
of pharmaceutical innovation

Proactive and expert, Novitom is your preferred partner to support innovation and the development of your solid formulations using new, sensitive, and reliable approaches.

Our approach, based on the use of advanced imaging and structural characterisation techniques, enable the visualisation of tablets and other solid dosage forms in 3D at high-resolution.

We bring value in understanding solid forms behaviour in dissolution, analysing polymorphic forms at the grain level, and revealing the distribution of the active ingredient, even at very low concentrations.

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Caracterisation of solid pharmaceutical dosage forms

  • 3D granular microstructure of a tablet or granules without cutting or marking
  • Homogeneity of active ingredient distribution
  • Identification and morphology of defects in 3D: size, shape, position, connectivity
  • Analysis of the coating on the finished product, without cutting: thickness, roughness, homogeneity
  • Analysis of the integrity of capsules, tablets, and gums, even within the product packaging
  • 3D evolution of the microstructure – grains and pores – during dissolution
  • Samples are placed under conditions of use: temperature, humidity, compression

Cutting-edge techniques at the service of galenic innovation

The advantages of NOVITOM

Reliable and rapid analyses

Analyses carried out on state-of-the-art equipment by a team of experts.

Tailor-made approach

An approach tailored to your constraints, with a technical contact person who supports you from start to finish.

Clear results

Actionable results thanks to detailed reports and 3D visuals that facilitate decision-making.

Case studies of tablets and solid pharmaceutical dosage forms

The microstructure of tablets revealed by synchrotron X-rays

The microstructure of tablets revealed by synchrotron X-rays

A recent study conducted by Xploraytion, Novitom, Merck and…

The dissolution of coated tablets highlighted by X-ray microtomography

The dissolution of coated tablets highlighted by X-ray microtomography

Which phenomena are decisive in oral drug release from…

Samples types

  • Tablets, gums, lozenges, capsules, and caplets, with or without packaging
  • Granules
  • Implants and devices for controlled drug release
  • Controlled drug delivery systems
  • Powders and lyophilized powders
  • Suppositories and vaginal suppositories
  • Transdermal patches