X-ray tomography is now a reference method for non-destructive three-dimensional imaging. Its principle is based on capturing a large number of X-ray images from different angles, which are then combined digitally to reconstruct the internal structure of an object. Tomography, which has become essential in various fields such as material
A recent study conducted by Xploraytion, Novitom, Merck, and their partners demonstrates how synchrotron X-ray microtomography (SR-µCT) is transforming the analysis of pharmaceutical tablets. Published in the International Journal of Pharmaceutics, this study shows how the internal structures of tablets can be visualized in 3D and in real time. The
X-ray microtomography (micro-CT) images enable advanced particle size analysis, allowing the characterisation of the size, shape, and spatial distribution of particles, pores, or inclusions that make up one or more phases of a material. The material is probed “as is” , i.e. without the need for conditioning. The three-dimensional nature
Which phenomena are decisive in oral drug release from coated tablets? Key findings from a research work by Univ. Lille, INSERM, CHU Lille, Novitom, Merck Sharp & Dohme Through dynamic microtomography, the study revealed the existence of air-filled pores in the core of coated pellets . When the liquid penetrates,
On September 13, 2023, Rigaku hosted an episode of its Ask the Expert webinar series, featuring Dr. Awen Autret, R&D Engineer at Novitom. The session, titled “Virtual Tomography – Optimizing Data Acquisition Parameters Without a CT Scanner”, explored how advanced simulation can accelerate and enhance X-ray CT imaging workflows. Dr.
Congratulations to our colleague Danilo Rosa Nunes, PhD in Pharmaceutical Science! He won thes Young Researcher Award following the competition organised as part of the Lipids and Cosmetics 2022 conference. The awarded work is described in a poster: ”Quantitative structural analysis of Human Stratum Corneum lamellar structure by Computational Simulation of
